Frances M Saccoccio

Frances M Saccoccio, M.D., Ph.D.

Clinical Assistant Professor

Business Phone: (352) 294-8591
Business Email:

About Frances M Saccoccio

Frances Saccocio, MD, PhD, is a clinical assistant professor with the division of pediatric infectious diseases at the University of Florida who practices at UF Health. As a pediatric infectious disease expert at UF Health Shands Children’s Hospital, she is committed to the prevention, diagnosis and treatment of infectious diseases that affect children from birth to age 21.

Dr. Saccoccio obtained her medical and doctorate degrees at Virginia Commonwealth University School of Medicine in Richmond, Virginia. She then went on to complete her residency in general pediatrics at Virginia Commonwealth University Health System and her fellowship in pediatric infectious diseases at Duke University Medical Center in Durham, North Carolina. Her primary research interest is in the prevention and treatment of cytomegalovirus (CMV). Outside of work Dr. Saccoccio enjoys hiking with her husband and running marathons.


Derfner Research Foundation Award
2018-2019 · Derfner Research Foundation
Thrasher Research Foundation Early Career Award
2018-2019 · Thrasher Research Foundation
NIH Loan Repayment
2017-2019 · NIH Division of Pediatric Research
Pediatric Infectious Diseases Society Fellowship Award funded by the National CMV Foundation
2017-2019 · Pediatric Infectious Diseases Society

Board Certifications

  • General Pediatrics
    American Board of Pediatrics
  • Pediatric Infectious Diseases
    American Board of Pediatrics

Clinical Profile

  • Pediatrics
  • Pediatric Infectious Disease
Areas of Interest
  • Cytomegalovirus (CMV) infection
  • Infectious diseases

Research Profile

Open Researcher and Contributor ID (ORCID)


Areas of Interest
  • Congenital cytomegalovirus
  • Infections in immune compromised patients
  • Perinatal infections


A case report of primary amebic meningoencephalitis in North Florida
IDCases. 25 [DOI] 10.1016/j.idcr.2021.e01208. [PMID] 34307045.
An uncommon cause of soft tissue and knee infection after penetrating injury in a non-immunocompromised adolescent male
SAGE Open Medical Case Reports. 9 [DOI] 10.1177/2050313×211034683.
Prenatal Treatment of Congenital Cytomegalovirus With Valganciclovir: A Case Report.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 71(9):2506-2508 [DOI] 10.1093/cid/ciaa305. [PMID] 32198512.
Dual targeting: Combining costimulation blockade and bortezomib to permit kidney transplantation in sensitized recipients.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 19(3):724-736 [DOI] 10.1111/ajt.15067. [PMID] 30102844.
Humoral Immune Correlates for Prevention of Postnatal Cytomegalovirus Acquisition.
The Journal of infectious diseases. 220(5):772-780 [DOI] 10.1093/infdis/jiz192. [PMID] 31107951.
Pretransplant Desensitization with Costimulation Blockade and Proteasome Inhibitor Reduces DSA and Delays Antibody-Mediated Rejection in Highly Sensitized Nonhuman Primate Kidney Transplant Recipients.
Journal of the American Society of Nephrology : JASN. 30(12):2399-2411 [DOI] 10.1681/ASN.2019030304. [PMID] 31658991.
A cytomegalovirus DNA vaccine induces antibodies that block viral entry into fibroblasts and epithelial cells.
Vaccine. 33(51):7328-7336 [DOI] 10.1016/j.vaccine.2015.10.078. [PMID] 26597035.
Neutralizing activity of saliva against cytomegalovirus.
Clinical and vaccine immunology : CVI. 18(9):1536-42 [DOI] 10.1128/CVI.05128-11. [PMID] 21795465.
Peptides from cytomegalovirus UL130 and UL131 proteins induce high titer antibodies that block viral entry into mucosal epithelial cells.
Vaccine. 29(15):2705-11 [DOI] 10.1016/j.vaccine.2011.01.079. [PMID] 21310190.
CD8 T cell cross-reactivity networks mediate heterologous immunity in human EBV and murine vaccinia virus infections.
Journal of immunology (Baltimore, Md. : 1950). 184(6):2825-38 [DOI] 10.4049/jimmunol.0902168. [PMID] 20164414.
Protection against vaccinia virus challenge by CD8 memory T cells resolved by molecular mimicry.
Journal of virology. 81(2):934-44 [PMID] 17079318.
View on: PubMed


Fellowship in Pediatric Infectious Diseases
2019 · Duke University Medical Center
Residency in Pediatrics
2016 · Virginia Commonwealth University Health System
Medical School and Doctorate
2013 · Virginia Commonwealth University

Contact Details

(352) 294-8591