Lawrence R Shoemaker

Lawrence R Shoemaker, M.D.

Clinical Associate Professor And Chief

Department: MD-PEDS-NEPHROLOGY
Business Phone: (352) 273-9180
Business Email: lrshoe01@peds.ufl.edu

About Lawrence R Shoemaker

Dr. Shoemaker is an Associate Professor and Chief of Pediatric Nephrology. He is also the director of the UF Pediatric Dialysis Unit. His clinical interests include acute and chronic renal replacement therapy, fluid and electrolyte disorders and genetic kidney disease.

Accomplishments

Celebrating Better Service Award
2011 · Kosair Children's Hospital
Physician of the Quarter
2011 · Kosair Children's Hospital
Top 5 Clinical Teacher of the Year
2011 · University of Louisville
Top 5 Clinical Teacher of the Year
2009 · University of Louisville
Top 5 Clinical Teacher of the Year
2008 · University of Louisville

Teaching Profile

Courses Taught
2018
MDC7400 Pediatric Clerkship

Board Certifications

  • Pediatric Nephrology
    American Board of Pediatrics
  • Pediatrics
    American Board of Pediatrics

Clinical Profile

Specialties
  • Pediatrics
Areas of Interest
  • Chronic kidney disease
  • Electrolytes
  • Fluid imbalance
  • Kidney disease – resources
  • Renal

Research Profile

Areas of Interest
  • Mathematical modeling of dialysis adequacy
  • Mechanisms of acute kidney injury
Open Researcher and Contributor ID (ORCID)

0000-0001-5088-9774

Publications

2024
Dysregulation of kidney proteases in the pathogenesis of hypertension following unilateral nephrectomy in juvenile mice.
American journal of translational research. 16(2):544-556 [PMID] 38463588.
2024
Functional and metabolomic analysis of urinary extracellular vesicles from juvenile mice with renal compensatory hypertrophy.
Biochimica et biophysica acta. Molecular basis of disease. 1870(5) [DOI] 10.1016/j.bbadis.2024.167096. [PMID] 38499276.
2024
Thrombotic microangiopathy following systemic AAV administration is dependent on anti-capsid antibodies.
The Journal of clinical investigation. 134(1) [DOI] 10.1172/JCI173510. [PMID] 37988172.
2023
Does kidney biopsy in pediatric lupus patients “complement” the management and outcomes of silent lupus nephritis? Lessons learned from a pediatric cohort.
Pediatric nephrology (Berlin, Germany). 38(8):2669-2678 [DOI] 10.1007/s00467-022-05859-w. [PMID] 36688943.
2022
Extracellular vesicles from focal segmental glomerulosclerosis pediatric patients induce STAT3 activation and mesangial cell proliferation.
PloS one. 17(11) [DOI] 10.1371/journal.pone.0274598. [PMID] 36374911.
2022
IgA-dominant infection-associated glomerulonephritis in the pediatric population.
Pediatric nephrology (Berlin, Germany). 37(3):593-600 [DOI] 10.1007/s00467-021-05245-y. [PMID] 34453602.
2021
Attention to detail: not simple bed wetting-Hinman-Allen syndrome.
Journal of nephrology. 34(1):247-250 [DOI] 10.1007/s40620-020-00810-4. [PMID] 32720135.
2020
An international cohort study of autosomal dominant tubulointerstitial kidney disease due to REN mutations identifies distinct clinical subtypes.
Kidney international. 98(6):1589-1604 [DOI] 10.1016/j.kint.2020.06.041. [PMID] 32750457.
2020
BK virus encephalitis and end-stage renal disease in a child with hematopoietic stem cell transplantation.
Pediatric transplantation. 24(6) [DOI] 10.1111/petr.13739. [PMID] 32412694.
2020
Hypothyroidism Due to Iodine Overload in Children Receiving Peritoneal Dialysis: A Report of 4 Cases.
American journal of kidney diseases : the official journal of the National Kidney Foundation. 76(6):889-892 [DOI] 10.1053/j.ajkd.2020.02.448. [PMID] 32471796.
2017
Tight metabolic control plus ACE inhibitor therapy improves GSD I nephropathy.
Journal of inherited metabolic disease. 40(5):703-708 [DOI] 10.1007/s10545-017-0054-2. [PMID] 28612263.
2012
Reduced elastogenesis: a clue to the arteriosclerosis and emphysematous changes in Schimke immuno-osseous dysplasia?
Orphanet journal of rare diseases. 7 [DOI] 10.1186/1750-1172-7-70. [PMID] 22998683.
2012
Severe calcification of the aorta (porcelain aorta) associated with sarcoidosis in a pediatric heart transplant recipient.
Pediatric transplantation. 16(5):E162-6 [DOI] 10.1111/j.1399-3046.2011.01557.x. [PMID] 21883745.
2012
Update of PAX2 mutations in renal coloboma syndrome and establishment of a locus-specific database.
Human mutation. 33(3):457-66 [DOI] 10.1002/humu.22020. [PMID] 22213154.
2010
Schimke immunoosseous dysplasia: defining skeletal features.
European journal of pediatrics. 169(7):801-11 [DOI] 10.1007/s00431-009-1115-9. [PMID] 20013129.
2009
Exercise testing is useful to screen for residual coarctation in children.
Pediatric cardiology. 30(6):763-7 [DOI] 10.1007/s00246-009-9415-4. [PMID] 19449057.
2008
Alemtuzumab (Campath-1H) induction in a pediatric heart transplant: successful outcome and rationale for its use.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 27(2):242-4 [DOI] 10.1016/j.healun.2007.11.569. [PMID] 18267235.
2008
Midaortic syndrome presenting as neonatal hypertension.
Pediatric cardiology. 29(5):1000-1 [PMID] 18060446.
2007
A three-year-old with persistent hypokalemia.
The Journal of pediatrics. 151(6):696-9 [PMID] 18035156.
2007
Acute sirolimus pulmonary toxicity in an infant heart transplant recipient: case report and literature review.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 26(3):296-8 [PMID] 17346635.
2006
Cardiac transplantation for pediatric giant cell myocarditis.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 25(4):474-8 [PMID] 16563980.
2004
Angiotensin II reduces calcium uptake into bone.
Pediatric nephrology (Berlin, Germany). 19(1):33-5 [PMID] 14648327.
2004
Collapsing glomerulopathy in a 16-year-old girl with pulmonary tuberculosis: the role of systemic inflammatory mediators.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society. 7(2):166-70 [PMID] 15022071.
2001
Genotype/phenotype observations in African Americans with Bartter syndrome.
The Journal of pediatrics. 139(1):105-10 [PMID] 11445802.
2000
Bartter and Gitelman syndromes.
Advances in pediatrics. 47:223-48 [PMID] 10959445.
2000
Urea kinetic analysis of automated peritoneal dialysis allows calculation of a CAPD-equivalent Kt/V(urea).
Kidney international. 58(3):1318-24 [PMID] 10972696.
1999
Conjunctive effects of fibroblast growth factor and glycosaminoglycan on bone metabolism in neonatal bartter syndrome.
Pediatric research. 45(5 Pt 1):726-32 [PMID] 10231872.
1999
Expanding role of bisphosphonate therapy in children.
The Journal of pediatrics. 134(3):264-7 [PMID] 10064659.
1999
Steroid-refractory neonatal eosinophilic pneumonia responsive to cyclosporin A.
American journal of respiratory and critical care medicine. 160(3):1019-22 [PMID] 10471634.
1998
Humoral factor in children with neonatal Bartter syndrome reduces bone calcium uptake in vitro.
Pediatric nephrology (Berlin, Germany). 12(5):371-6 [PMID] 9686954.
1995
Precise determination of the absorptive component of urinary calcium excretion using stable isotopes.
Pediatric nephrology (Berlin, Germany). 9(3):295-7 [PMID] 7632514.
1994
Hereditary angioneurotic oedema: characterization of plasma kinin and vascular permeability-enhancing activities.
Clinical and experimental immunology. 95(1):22-8 [PMID] 8287604.
1993
Calcium kinetics in the hyperprostaglandin E syndrome.
Pediatric research. 33(1):92-6 [PMID] 8433868.
1990
Vitamin A in cystic fibrosis: case report and review of the literature.
Journal of pediatric gastroenterology and nutrition. 10(2):265-9 [PMID] 2406407.

Grants

Mar 2024 ACTIVE
AN OPEN-LABEL, NONRANDOMIZED, MULTICENTER EXTENSION STUDY TO EVALUATE THE LONG-TERM SAFETY AND EFFICACY OF PEGCETACOPLAN IN PARTICIPANTS WITH C3 GLOMERULOPATHY OR IMMUNE-COMPLEX MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS
Role: Principal Investigator
Funding: APELLIS PHARMACEUTICALS
Jul 2022 ACTIVE
CMS Comprehensive Children's Kidney Failure Center – COQVW Renewal for FY22-25
Role: Principal Investigator
Funding: FL DEPT OF HLTH CHILDRENS MED SERVS via US DEPT OF HLTH AND HUMAN SER
Jun 2022 ACTIVE
A PHASE 3, RANDOMIZED, PLACEBO-CONTROLLED, DOUBLE-BLINDED, MULTICENTER STUDY TO EVALUATE THE EFFICACY AND SAFETY OF PEGCETACOPLAN IN PATIENTS WITH C3 GLOMERULOPATHY OR IMMUNE-COMPLEX MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS
Role: Principal Investigator
Funding: WORLDWIDE CLINICAL TRIALS via APELLIS PHARMACEUTICALS
Jul 2019 – Jun 2022
CMS Comprehensive Children's Kidney Failure Center through FY2022
Role: Principal Investigator
Funding: FL DEPT OF HLTH CHILDRENS MED SERVS via US HLTH RESOURCES AND SERV ADMN
Jul 2015 – Jun 2019
CMS Comprehensive children kidney failure center
Role: Principal Investigator
Funding: FL DEPT OF HLTH CHILDRENS MED SERVS

Contact Details

Phones:
Business:
(352) 273-9180
Emails:
Addresses:
Business Mailing:
PO Box 100296
GAINESVILLE FL 32610
Business Street:
Department of Pediatrics
Division of Pediatric Nephrology
1600 SW Archer Road
Gainesville FL 32607